title : 문헌 38 Silic acid 의 대장균 감염억제
name : 관리자date : 2010-09-01 00:00:00hits : 1083

Escherichia coli strains binding neuraminyl alpha 2-3 galactosides.

Parkkinen J, Finne J, Achtman M, Väisänen V, Korhonen TK.


A total of 46 E. coli strains showing mannose-resistant, P-blood-group independent hemagglutination of human erythrocytes were tested for binding to neuraminic acid. Nine of the strains completely lost their hemagglutination activity after the erythrocytes were treated with neuraminidase. To characterize the receptor structure, different neuraminic acid containing glycoproteins, their desialylated derivatives and neuraminyl oligosaccharides were tested for hemagglutination inhibition. These studies showed that the nine strains had binding specificity for alpha 2-3 linked neuraminic acid.

PMID: 6340671 [PubMed - indexed for MEDLINE]

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